sheldon
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Ski,
Are you referring to Virtuoso IC614? Spectre is a simulator. The basic recommendation would be to up version to the most recent IC615 ISR release. There have been a significant enhancements in to statistical analysis tools, in particular, support for confidence intervals and Monte Carlo auto-stop are new for IC615. I think that the issue of the appropriate number of samples to select is complex question, which is why using some of the new tools, such as, Monte Carlo auto-stop, might be useful. Another option is to use one of the alternative sampling methods, for example, orthogonal sampling. Using orthogonal sampling should give better estimates with fewer points. Also since you are simulating a sense amp, you might want to consider using High Sigma Yield estimation since you probably are looking for more than 3 sigma yield.
Best Regards,
Sheldon
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