Geoffrey_Coram
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I'm not sure how you expect someone to help you, with the tiny bit of information you've shared -- oh, yes! Spectre doesn't allow any supply voltage except 1.8, so you can't change it! (Kidding.)
There are some circuits that are designed to be insensitive to the supply voltage. Could this be your problem? You haven't told us anything about your circuit.
Are you sure the supply voltage you changed is the main supply? How much did you change it, and how much did the power change?
Is your circuit actually operating? Have you looked at the waveforms to verify this?
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