Stefan
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That strongly depends on the filter characteristics you chose for your system. You need to use 2 frequencies that can travel through your input filters, across your LNA/Mixer stages and so on, until they reach (downconverted) the lowpass filters and the ADC. The lowpass filters and bandwidth of your LNA/mixer combination specify the allowed distance between the two carriers, your simulation time requirements specify the minimum distance needed for effective simulation. However, when characterizing a wideband sytem, you should consider using 2.5GHz instead of 2.44GHz for easier use of fractional parameters ...
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